PSY FPX 6110 Assessment 1 Annotated Bibliography-Psychedelic Therapy Studies
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Assessment Overview:
PSY FPX 6110 Assessment 1: provides an annotated bibliography on psychedelic remedy studies, pressing exploration on substances like 5- MeO- DMT, LSD, psilocybin, and MDMA. The studies explore remedial goods on depression, anxiety, PTSD, social connectedness, and transformative gests . Findings show that psychedelics, under controlled settings, can ameliorate internal health, enhance mood, and foster social and particular growth. The exploration emphasizes structured administration, ethical oversight, and implicit clinical operations. Overall, the assessment underscores the arising part of psychedelic remedy in cerebral treatment and intervention.
How to Pass PSY FPX 6110 Assessment 1 Annotated Bibliography-Psychedelic Therapy Studies
- Define the “Gold Standard”: Note that many of these studies are double-blind, placebo-controlled trials, which is the highest level of clinical evidence.
- Focus on 5-HT2A: For the LSD and Psilocybin studies, explicitly mention the 5-HT2A serotonin receptor, as it is the primary target for most classic psychedelics.
- The PTSD Breakthrough: Highlight that the Mitchell (2021) study was a Phase 3 trial—this is the final step before a drug is considered for FDA approval.
- Differentiate the Substances: Be clear that MDMA (an empathogen) works differently than Psilocybin (a classic psychedelic), even though both are used in therapy.
- Mention Set and Setting: Acknowledge that in these studies, the “therapy” is just as important as the “drug.” The psychosocial support is a key variable.
- Highlight Long-Term Efficacy: Note that Griffiths (2016) found sustained results at 6 months, which is a major advantage over daily medications like SSRIs.
- Neuroplasticity vs. Mystical Experience: Mention that these studies look at both the biological (brain changes) and subjective (mystical significance) aspects of healing.
- Correct Technical Terms: Use the term “Naturalistic Setting” when referring to non-laboratory environments, and “Remission” when symptoms disappear.
- DOI Verification: Double-check that all DOIs in your reference list are active and correctly formatted as live links.
- Ethical Considerations: Briefly note that all these studies required IRB (Institutional Review Board) approval due to the controlled nature of the substances.
Sample Assessment:
Annotated Bibliography
Davis, A. K., So, S., Lancelotta, R., Barsuglia, J. P., & Griffiths, R. R.( 2019). 5- methoxy– dimethyltryptamine( 5- MeO- DMT) used in a natural group setting is associated with unintended advancements in depression and anxiety. The American Journal of medicine and Alcohol Abuse, 45( 2), 161 – 169. https// doi.org/10.1080/00952990.2018.1545024
Davis, So, Lancelotta, Barsuglia, and Griffiths( 2019) delved into the application of 5- methoxy– dimethyltryptamine( 5- MeO- DMT) in a collaborative setting, revealing unintended ameliorations in depression and anxiety. The study anatomized tone- reported situations of depression and anxiety among individualities consuming 5- MeO- DMT in a group terrain characterized by structured dosing, procedures, and support mechanisms. The findings suggested that following the use of 5- MeO- DMT, there were reported advancements in symptoms of depression and anxiety among actors. These advancements were associated with increased spiritual significance and particular meaning attributed to the experience.
Duerler, P., Schilbach, L., Stämpfli, P., Vollenweider, F. X., & Preller, K. H.( 2020). LSD- convinced increases in social adaption to opinions analogous to one’s own are associated with stimulation of serotonin receptors. Scientific Reports, 10( 1), 12181. https//doi.org/10.1038/s41598-020-68899-y
PSY FPX 6110 Assessment 1 Annotated Bibliography-Psychedelic Therapy Studies
Duerler et al.( 2020) delved into the impact of LSD on social adaptation to opinions harmonious with one’s own, expounding the part of serotonin receptors in social influence processing. The double-eyeless arbitrary crossover study involved 24 levies who entered either a placebo, LSD( 100 micrograms), or a 5HT2A receptor antagonist plus LSD( 100 micrograms) over three sessions. The results indicated that LSD eased social adaption, particularly when individualities encountered opinions aligned with their own. This effect was identified with jacked exertion in the frontal medium prefrontal cortex during social feedback processing, furnishing perceptivity into the neuropharmacological mechanisms underpinning social cognitive geste
.
Forstmann, M., Yudkin, D. A., Prosser, A. M., Heller, S. M., & Crockett, M. J.( 2020). Transformative experience and social connectedness intervene the mood- enhancing goods of psychedelic use in natural settings. Proceedings of the National Academy of lores, 117( 5), 2338 – 2346. https// doi.org/10.1073/pnas.1918477117
Forstmann et al.( 2020) examined the interceding places of transformative gists and social connectedness in the mood- enhancing goods of psilocybin and other psychedelics in natural settings. The three- time study, comprising 1,225 actors across multiple mass gatherings, employed field studies and questionnaire assessments. The findings suggested that recent psychedelic use was associated with heightened transformative gestures and social connectedness, which in turn intermediated advancements in positive mood. This study underscores the eventuality of psychedelics to induce particular metamorphosis and enhance social cohesion in natural settings, with ethical blessing from the Oxford Central Research Ethics Committee.
PSY FPX 6110 Assessment 1 Annotated Bibliography-Psychedelic Therapy Studies
Griffiths, R. R., Johnson, M. W., Carducci, M. A., Umbricht, A., Richards, W. A., Richards, B. D., Cosimano, M. P., & Klinedinst, M. A.( 2016). Psilocybin produces substantial and sustained diminishments in depression and anxiety in cases with life- hanging cancer A randomized double-eyeless trial. Journal of Psychopharmacology( Oxford), 30( 12), 1181 – 1197. https// doi.org/10.1177/0269881116675513
Griffiths et al.( 2016) delved the goods of psilocybin on depression and anxiety symptoms in cancer cases through a randomized double-eyeless trial. The study involved 51 cases with life- hanging judgments who entered either a low or high cure of psilocybin in across-over design. Significant reductions in depression and anxiety, coupled with increased life meaning and sanguinity, were observed following high- cure psilocybin administration. These goods were sustained at the 6- month follow- up, suggesting the remedial eventuality of psilocybin in easing cerebral torture in cancer cases.
Mitchell, J. M., Bogenschutz, M., Lilienstein, A., Harrison, C., Kleiman, S., Parker- Guilbert, K., Ot’alora G, M., Garas, W., Paleos, C., Gorman, I., Nicholas, C., Mithoefer, M., Carlin, S., Poulter, B., Mithoefer, A., Quevedo, S., Wells, G., Klaire, S. S., van der Kolk, B., Tzarfaty, K., Doblin, R.( 2021). MDMA- supported remedy for severe PTSD A randomized, double-eyeless, placebo- controlled phase 3 study. Nature Medicine, 27( 6), 1025 – 1033. https//doi.org/10.1038/s41591-021-01336-3
PSY FPX 6110 Assessment 1 Annotated Bibliography-Psychedelic Therapy Studies
Mitchell et al.( 2021) conducted a phase 3 trial to assess the efficacity and safety of MDMA- supported remedy for severe PTSD. Ninety actors were randomized to admit either MDMA remedy or a placebo, alongside introductory and integrative sessions. Significant reductions in PTSD symptoms were observed in the MDMA group compared to the placebo, with some cases achieving absolution after just one or two sessions. This study highlights the promising remedial eventuality of MDMA- supported remedy in individualities with severe PTSD, warranting farther clinical evaluation.
References (APA 7 Format)
- Davis, A. K., So, S., Lancelotta, R., Barsuglia, J. P., & Griffiths, R. R. (2019). 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) used in a naturalistic group setting is associated with unintended improvements in depression and anxiety. The American Journal of Drug and Alcohol Abuse, 45(2), 161–169. https://doi.org/10.1080/00952990.2018.1545024
- Duerler, P., Schilbach, L., Stämpfli, P., Vollenweider, F. X., & Preller, K. H. (2020). LSD-induced increases in social adaptation to opinions similar to one’s own are associated with stimulation of serotonin receptors. Scientific Reports, 10(1), 12181. https://doi.org/10.1038/s41598-020-68899-y
- Forstmann, M., Yudkin, D. A., Prosser, A. M., Heller, S. M., & Crockett, M. J. (2020). Transformative experience and social connectedness mediate the mood-enhancing effects of psychedelic use in naturalistic settings. Proceedings of the National Academy of Sciences, 117(5), 2338–2346. https://doi.org/10.1073/pnas.1918477117
- Griffiths, R. R., Johnson, M. W., Carducci, M. A., Umbricht, A., Richards, W. A., Richards, B. D., Cosimano, M. P., & Klinedinst, M. A. (2016). Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial. Journal of Psychopharmacology (Oxford), 30(12), 1181–1197. https://doi.org/10.1177/0269881116675513
- Mitchell, J. M., Bogenschutz, M., Lilienstein, A., Harrison, C., Kleiman, S., Parker-Guilbert, K., Ot’alora G, M., Garas, W., Paleos, C., Gorman, I., Nicholas, C., Mithoefer, M., Carlin, S., Poulter, B., Mithoefer, A., Quevedo, S., Wells, G., Klaire, S. S., van der Kolk, B., Tzarfaty, K., … Doblin, R. (2021). MDMA-assisted therapy for severe PTSD: A randomized, double-blind, placebo-controlled phase 3 study. Nature Medicine, 27(6), 1025–1033. https://doi.org/10.1038/s41591-021-01336-3
Rubric Breakdown
| Criteria | Proficient (Target) | Needs Improvement |
| Selection of Sources | Includes high-impact, peer-reviewed studies (MDMA, Psilocybin, LSD) relevant to the prompt. | Sources are outdated, non-scholarly, or not directly related to psychedelic therapy. |
| Summarization | Concisely explains the methodology, participants, and primary findings of each study. | Summaries are vague or fail to mention specific results (e.g., p-values or remission rates). |
| Critical Analysis | Discusses the implications of the research, such as neurobiological mechanisms or long-term efficacy. | Merely summarizes without explaining why the study is important for clinical practice. |
| APA Formatting | Citations and references follow APA 7th Edition precisely, including DOIs. | Frequent errors in italics, capitalization, or DOI formatting. |
| Academic Clarity | Uses precise clinical terminology (e.g., “5-HT2A receptor,” “Double-blind”). | Uses non-standard or confusing language (e.g., “Collaborative setting” for “Naturalistic”). |
Step-by-Step Guide
- Select Studies Identify peer- reviewed exploration on psychedelic curatives in controlled or natural settings.
- epitomize crucial Findings Note remedial goods on internal health, mood, and social issues.
- dissect styles punctuate study designs, tablets, settings, and party demographics.
- estimate Counteraccusations Consider clinical, social, and ethical significance of the findings.
- Cite duly gives full references with DOIs for each study reviewed.
Frequently Asked Questions
Q What’s the focus of this PSY FPX 6110 Assessment 1?
Reviewing studies on the remedial goods of psychedelics.
Q Which substances were studied?
5- MeO- DMT, LSD, psilocybin, and MDMA.
Q What internal health conditions were targeted?
Depression, anxiety, PTSD, and social functioning.
Q Are psychedelics long- lasting?
Yes, some studies show sustained advancements months after remedy.
Q Is structured administration important?
Yes, controlled dosing and ethical oversight are pivotal for safety and efficacity.
Integrity Note
Note: Only use this assessment example for learning and structure purpose. Do not submit as your own work.
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